Kathleen Louisa Brandhofer was born in Vienna and grew up in Berlin. The singer with Austrian-American roots comes from a musical family and received her first musical training at the age of 4 years at the piano. She studied arts management and music at Salem College (USA) and completed her double degree with honors (magna cum laude). In 2015, she completed her studies in vocal pedagogy as well as vocal and opera performance at the University of the Arts Berlin (UdK). She attended master classes with Eric Schneider, Malcolm Martineau, Prof. Helen Donath and Prof. Konrad Jarnot (International Summer Academy Mozarteum Salzburg) and the art song classes of Prof. Wolfram Rieger (Hochschule für Musik "Hanns Eisler"), Hendrik Heilmann (UdK), Prof. Jonathan Alder (French song) and Prof. Axel Bauni (contemporary song).

Kathleen has appeared regularly as a soloist and chamber musician in Germany, Austria, Great Britain, and the USA. She co-founded the Lied duo PianoCantando and was a scholarship recipient of the Association Yehudi Menuhin LiveMusicNow with national and international concerts. She performed regular recitals in the Spiegelsaal at Clärchens Ballhaus, and for the Mendelssohn Society Berlin at the Mendelssohn Remise. Furthermore, she sang at the University of the Arts and at the Lange Nacht der Opern und Theater Berlin in Paul Hindemith's comic opera There and Back in the lead role of "Helene". In 2015 she took on the role of Public Opinion in Offenbach's Orpheus in the Underworld under the baton of Steffen Tast and with members of the Berlin Radio Symphony Orchestra.

Since 2014 she has been artistic director of ART DE L'AUTRE in Berlin. 

She has been a member of the Chorus of the Landestheater Linz since January 2016.